Louis Theroux

Louis immerses himself in the world of Ohio's state psychiatric hospitals, meeting patients who have committed crimes - at times horrifically violent - while in the grip of severe mental illness. They have been found not guilty by reason of insanity and ordered by the courts to secure psychiatric facilities to receive the treatment that it is hoped will, one day, lead to their reintegration back into society.

In the first of two episodes, Louis spends time with patients attempting to come to terms with their crimes and the clinicians entrusted with helping to make them safe. And he investigates the difficult question - when is a patient with a serious crime in their past ready to be returned to the outside world?

Louis immerses himself in the world of Ohio's state psychiatric hospitals, meeting patients who have committed crimes - at times horrifically violent - while in the grip of severe mental illness. They have been found not guilty by reason of insanity and ordered by the courts to secure psychiatric facilities to receive the treatment that it is hoped will, one day, lead to their reintegration back into society.

In the second episode of this two-part series, Louis spends time with patients whose personalities are so intertwined with their illness that it makes them more difficult to treat. In doing so, he examines the grey area between criminal actions and medical symptoms, and investigates how we define insanity.

Louis Theroux travels to San Francisco where a group of pioneering medical professionals help children who say they were born in the wrong body transition from boy to girl or girl to boy at ever younger ages.

At the Child and Adolescent Gender Center at UCSF Hospital Louis meets children who have been diagnosed with gender dysphoria. Louis is told that children as young as three can show signs of rejecting the gender they were assigned at birth, leaving parents with a difficult dilemma - do they start transitioning a child who is still developing their own identity or do they wait and risk making the change once their body has gone through the transformations of puberty?

It is a decision that can be the start of a complex series of medical interventions, from puberty blockers to hormone replacement therapy and eventually gender reassignment surgery. Louis spends time with children and their families as they negotiate their way along this life-changing journey.