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- TV Show Ended -
There is no Next Episode of Royal Pains planned.
HankMed treats the infomercial son and heir of a famous inventor, who worries about his father's mental state near the end and what it means to him; Jill's job is threatened when her mentor starts proceedings to have her fired.
Eddie R. has returned and has brought half the money that he owes his boys and Hank is having a hard time letting go of a grudge. Meanwhile, Blake Newberg is having heart palpitations and winds up in the hospital with "broken heart syndrome". Evan is trying to still get HankMed back in business with every scheme he has. A policeman John and his wife are in danger of a disease but like always the medical doctor is there to save the day. The crew at HankMed fight their own battles and each come to a interesting conclusion. Plus, Eddie R. gives the rest of the money back to Hank and Evan.
Hank treats an actor from a popular film franchise; Eddie R. lets it slip that he is going to be staying in the Hamptons for a longer time then anticipated.
Boris flies Hank to another country to assist in his radical medical treatment; Hank's temporary replacement makes a bad impression on Divya.
Hank and Evan are still in Cuba and Hank works desperately to save Boris when the clinical trial fails while dealing with a new patient, who is an enemy of the state. Divya struggles with her dislike of Dr. Peck and attempts to build a friendship with Jill.
Tucker's best friend is having unusual symptoms and Tucker feels it is due to alcohol abuse, but Hank has other ideas; Divya treats a wine maker who has headaches and can no longer taste food or drink.
Hank has competition when Emily Peck shows that she is just not a pretty face and that she is taking clients away from Hank. Meanwhile, Evan goes on a fake date with a wealthy girl who doesn't want her parents to know that she is dating an older guy. Evan has to see if Mack, an owner of a macaroni and cheese truck, has a neurological disorder or if he is just a jerk. Hank is accused of stealing one of Emily's patients and has to take Emily on a bet.
Hank's new patient turns out to be a bully from his youth; Evan decides to test Raj with a bachelor party; Divya and Jill spend a night on the town in New York.
Hank gets called to treat a seven year-old boy named Jake, whose symptoms appear to be directly related to his parents' divorce. Little does Hank know, Jake is the son of a high ranking official at Hamptons Heritage who is trying to close down the new clinic that Jill and Hank have made. Meanwhile, Emily and Hank get closer and Hank is starting to realize that maybe it is not the best plan.
Hank treats two lottery winners who have used their new fortune to move to the Hamptons.
Hank and Emily work together to treat a patient, but cannot agree on a treatment. Evan retaliates in a cyber war against Emily.
Hank treats a new patient who seems to fall a lot and asks a lot of questions about Hank's clients, especially Boris; Paige wants to meet Evan's family; Divya is confused about her feelings for a patient; Eddie's mysterious financial situation comes to a head.
Hank and Divya must figure out the cause of a mysterious illness breaking out on the set of a reality TV show; Evan takes advantage of Paige's generosity; Emily is invited to join HankMed, but she adds a twist; Hank begins treating Marisa while she hides the truth from Boris.
Hank treats a teenage music prodigy; Evan overhears a private conversation between his girlfriend's father and his house guests; Hank's father inadvertently causes friction between Hank and Emily; Divya continues to struggle with her feelings for Adam.
Hank treats a park ranger who is experiencing memory loss; Divya investigates the case of a storm chaser who has a history of bone fractures; Evan is irrationally afraid of a coming storm.
Jess Walsh leaves her high stress job in the city for a new beginning in the Hamptons, only to discover she is still feeling stressed, until Hank discovers a medical condition is to blame; Divya and Raj throw a party in New York for their friends; Marissa finally comes clean with Boris; Evan reveals his true feelings to Paige.
Hank has a new patient who has been diagnosed with MS, but Hank starts to have his doubts; Jill is offered a new job that will take her away from the Hamptons for six months; Divya and Raj take dance lessons for their impending wedding, but their instructor falls ill with an infectious disease; Eddie must make a life changing choice.