Dateline NBC

The suspicious death of Sarah Hartsfield's fifth husband leads investigators to a past filled with failed romances and wild allegations.

A house fire in South Texas kills Patricia Leigh Mills while her young son miraculously escapes. When Patricia Leigh's widower, Delbert, marries a woman named Allison less than 3 months later, her family becomes convinced he was involved. After Allison is arrested in a murder for hire plot, the question remains: did Delbert have help?

INTERVIEWS WITH: Delbert Mills, Patrick and Allison Salinas. 

Jimmie "Jay" Lee, a popular and beloved student at the University of Mississippi, vanishes from his apartment early one July morning and is never seen again.

Officials quickly rule a Georgia man's death a suicide after his wife tells authorities that he shot himself; believing there is more to the story, his family hires a private investigator, who uncovers troubling details.

When American University professor Sue Marcum is found murdered in her Maryland home, it appears to be a burglary gone wrong. But DNA from the scene tells a different story, pointing detectives toward someone she trusted. A years-long international hunt leads to a dramatic arrest and long-awaited justice. 

INTERVIEWS WITH: Sue's brother and his wife Alan and Barbara Marcum, FBI agents in Baltimore and Guadalajara, Prosecutors Debbie Feinstein and Ryan Wechsler, Defense Attorneys Meghan Brennan and Tatiana David, and others.

A wealthy podiatrist and his girlfriend plot to hire a hit man to kill his wife, but the would-be assassin alerts police; years later, a shocking new chapter after their release, as one of them allegedly attempts to revive the murder plot.

In her first interview since her mother's disappearance, "Today" co-anchor Savannah Guthrie recounts her family's fears and anguish, as well as their hope for answers.

Dateline examine the case of Brendan Banfield, the Virginia father found guilty earlier this year of murdering his wife and a second victim in a case that captured global attention.

The broadcast features never-before-seen footage of the family's au pair, Juliana Peres Magalhaes, speaking with police following the killings, prior to pleading guilty to charges related to the case. Authorities later revealed she had been involved in a relationship with Banfield and colluded with him in the murders.

Alice Ku, a California tutor, vanishes during a trip to Taiwan. Her family embarks on a desperate search spanning two continents but as investigators dig deeper, secrets emerge and a trail of digital evidence contradicts everything they thought they knew.

INTERVIEWS WITH: Alice's sisters Josephine and Grace Ku, civil attorneys Andrew Watters and Todd Davis, defense attorney Chuck Smith and more.

Found Guilty of Shooting His In-Laws, Serafini Maintains His Innocence & Says He Was ‘Crucified' By Jury: ‘The Justice System Failed'.

In his first-ever interview, former MLB pitcher Dan Serafini speaks with Dateline correspondent Keith Morrison. In the exclusive sit-down, Serafini maintains his innocence following his conviction earlier this year for shooting his in-laws at their home in Lake Tahoe. 

The broadcast also features interviews with key figures in the investigation, including Detective Daniel Meier, Placer County District Attorney Morgan Gire and more.

The latest developments in the case of mother-of-three Kouri Richins, who wrote a children's book about grief and was recently found guilty of murdering her husband, Eric.

Broadcast will include new interviews with key figures connected to the investigation including Richins' brother DJ, who is speaking publicly for the first time since the verdict.

When a law student is found murdered in her home, suspicion falls on someone close to her; for years, her family searches for answers as the case goes cold; decades later, renewed attention leads to an arrest and a dramatic courtroom twist.

When a mom is murdered in her driveway, detectives look to the warehouse where she works for answers; the convicted murderer speaks out for the first time.

Datelinereports on the latest twist in the Alex Murdaugh case, after his double murder convictions were overturned this week and a new trial was ordered for the murders of his wife and son. Craig Melvin speaks with key insiders about the developments, including Murdaugh's defense attorneys and the South Carolina attorney general. Dateline and Melvin have reported on this case since the beginning. 

Investigates the targeted murder of UnitedHealthcare CEO Brian Thompson in New York City and the subsequent manhunt for suspect Luigi Mangione, reported by Lester Holt. The episode examines evidence left at the scene—shell casings etched with "Deny. Delay. Depose."—and the national conversation regarding insurance claim practices. 

Ana Knezevich, a young, successful businesswoman, moves from South Florida to Madrid for a fresh start, but goesmissing just a few months after relocating. As her friends begin to search for her in Madrid, the FBI and Spanish police also investigate her disappearance and examine all possibilities, including her relationships. Friday's broadcast features exclusive network interviews with the detectives at the center of the case. 

INTERVIEWS WITH: Spanish detectives Remo Rodriguez and Emilio Tremino Leva, retired FBI agent Alex Montilla and Ana's friends Sanna Rameau and Eliza Romero.

After 25-year-old mom Regina Hicks is found dead in her car at the bottom of a pond, her death remains a mystery for nearly a quarter century. In a Dateline exclusive, the man who helped police bring the killer to justice discusses what happened that night and reveals why he waited so long to point police to the killer.

Mothers who lost their daughters at Camp Mystic in the catastrophic 2025 Texas floods sit down with Lester Holt to discuss their grief, their bond, and the investigation into what happened. 

The disappearance of a loving Kentucky mom leads police to question the three men closest to her; for the first time the lead investigator speaks out about the case.

When a fire breaks out at a mansion in an affluent New Jersey suburb, authorities find all four members of a successful and respected family deceased. After detectives learn of a second fire in a neighboring community just hours earlier, they uncover a shocking connection between the two blazes, launching an investigation that reveals a web of deception within the family.

INTERVIEWS WITH: Former Colts Neck Mayor JP Bartolomeo, Colts Neck resident and on-air reporter Monica Guy, detectives Richard Zarrillo and Lt. Christopher Brady, volunteer firefighters Carmelo LaMarca and Mike Whitehill, childhood friends of victims Jesse and Sophia Caneiro Asher and Ripley Burgess, assistant prosecutors Chris Decker and Nicole Wallace, and investigators Sgt. Stephen Vogt, Lt. Patrick Petruzziello, Lt. Nick Cattelona, and Captain Brian Weisbrot. 

When a woman finds a body on a rural road outside of Indianapolis, police learn the victim might have been poisoned with mushrooms.

INTERVIEWS WITH: The woman who found the body Jennie Thomas, friends of the victim Matt Tanner and his wife Chris and an expert in mycology and professor at Purdue University Dr. Mary Catherine Aime. 

When Dee Warner vanishes from her farm, her family is alarmed as her car is still in the driveway and her wedding ring was left behind. After three years of countless leads and no answers, a single X-ray image reveals the truth. 

INTERVIEWS WITH: Prosecuting attorney Jacqueline Wyse, assistant prosecuting attorney David McCreedy, retired road patrol deputy Austin Hall, Dee's brother Gregg Hardy, Dee's sister-in-law Shelley Hardy, Dee's nephew Parker Hardy, Dee's friend Kathryn Adams, defense attorney Mary Chartier and private investigator and attorney Billy Little.