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There is no Next Episode of My Cat from Hell planned.
A family becomes divided about a cat they rescued from New Orleans after Hurricane Katrina that is spraying the house and preventing them from getting new furniture.
Jackson must rescue Meki and Megan from their cycle of co-dependency before they're both kicked out of Megan's parent's place, or worse; Jackson tutors a bouncer on how to handle his sweet Tasmanian devil of a cat.
Skylar the cat is deathly afraid of her own tail; Jackson meets pair of guardians whose cat is destroying the house and attacking people at random.
Samantha is so afraid of her cat, Spike, that she keeps him in a cat box outside the house; cats in Brooklyn are making life difficult for a couple who watch them fight constantly.
Father and son in New York, N.Y. have been caring for a feral cat colony in their backyard, but now are in serious need of some help; Jackson tries to help Mike and Darcy's antisocial cat.
A foster family has serious difficulty with a cat they want to adopt and asks Jackson for help; Jackson meets the feline Internet sensation Lil' Bunny Sue Roux, who has no front legs.
A tour of the Koneko Cat Café in New York City. Also: Two roommates' cats keep attacking each other; a mother and daughter struggle to care for a frightened feral cat.
Jackson goes to a shelter in Los Angeles to help an overaggressive cat, and ultimately gets involved in a new concept for the facility.