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Leonard and Sheldon are brilliant physicists - geniuses in the laboratory, but socially challenged everywhere else. Enter beautiful, street-smart neighbor, Penny, who aims to teach them a thing or two about life. Despite their on-again, off-again relationship in the past, Leonard believes he's found true love with Penny. Even Sheldon has found a female companion, entering into a "Relationship Agreement" with neurobiologist Amy Farrah Fowler. In their free time, Leonard and Sheldon continue to enjoy frequent trips to the comic book store and fantasy role-playing games with their ever-expanding universe of friends, including fellow scientists Koothrappali, Wolowitz and Wolowitz's adorable microbiologist wife, Bernadette. (source: www.cbs.com)
After driving to Vegas to get married, Penny struggles with Leonard's confession that he kissed another girl. Also, Sheldon doesn't know how to act after Amy pushes pause on their relationship.
Leonard confronts the woman he kissed on the North Sea in an attempt to set Penny's mind at ease. Also, Sheldon films a special episode of "Fun with Flags" after his breakup with Amy, and Bernadette feels guilty about withholding a secret from Penny.
The guys surprise Leonard with a belated bachelor-party weekend in Mexico, but their plans hit a bump in the road when they get a flat tire on the way. Meanwhile, the girls lean on Penny to tell her unsuspecting family that she and Leonard eloped.
Sheldon learns of an impending change in his living arrangements and decides to revert back to 2003, a simpler time before he met Leonard and Penny. Also, Howard and Raj form a band to play at the Comic Book Store.
The guys take a fencing lesson from Barry Kripke and Sheldon finds himself in an awkward position when Kripke expresses interest in Amy. Also, when Stuart struggles to get female customers at the Comic Book Store, Penny, Amy and Bernadette come by to help him out.
In the midst of a nation-wide helium shortage, Sheldon and Leonard take desperate measures to get the supplies they need. Also, Penny and Bernadette download a dating app on Amy's phone to try and find her a new man.
While being interviewed for a documentary about Spock from "Star Trek", Sheldon struggles to suppress his emotions about his recent break-up with Amy. Also, Wolowitz and Bernadette butt heads over remodeling his childhood home.
When Leonard, Penny and Bernadette learn that Amy is going out on a dinner date, the trio set out to spy on her and the guy. Meanwhile, Sheldon recruits Raj and Howard to find a woman for him, since they were responsible for getting Amy and him together.
Sheldon and Amy try hanging out as friends when they spend Thanksgiving together at the aquarium. Also, Wolowitz reluctantly agrees to volunteer at the soup kitchen with Bernadette, Raj and Emily, and Penny discovers that Leonard knows more about her than she thought.
Sheldon has a revelation when he realizes why a song was stuck in his head. Also, Amy invites Dave over for dinner despite their previously awkward date, and Wolowitz and Koothrappali become obsessed with a fan of their band, "Footprints on the Moon".
As the guys prepare to go to the premiere of the new Star Wars movie, Sheldon plans a special event for Amy's birthday. Also, Leonard, Wolowitz, and Koothrappali must decide who will take their extra Star Wars movie ticket.
Penny gets more than she bargained for when Leonard agrees to meet with a psychiatrist on her behalf. Also, Sheldon and Koothrappali collaborate on an astronomical discovery, and Wolowitz and Bernadette can't believe what they are feeling after Stuart moves out.
After having to deal with a sick Sheldon, Leonard, Penny and the gang try to treat themselves to a Sheldon-free weekend.
Sheldon's thrilled when his Meemaw comes to visit, but his excitement quickly fades when she butts heads with Amy. Also, Raj meets a new girl at the comic book store who makes him question his relationship with Emily.
Sheldon and Amy host a live Valentine's Day episode of Fun with Flags, Leonard and Penny grapple with getting older, Howard and Bernadette find a surprise in their hot tub and Raj is torn between Emily and the cute girl he met at the Comic Bookstore.
When the gang finds out about Bernadette's pregnancy, they celebrate by singing karaoke. Also, Bernadette is concerned when Wolowitz freaks out over her pregnancy announcement, and Wolowitz is convinced he must make more money to provide for the baby.
After more than nine years together, the gang finally celebrates Sheldon's birthday, surprising him with a special guest.
Leonard, Sheldon, and Wolowitz run into problems when they file for a patent for their infinite persistence gyroscope. Also, Penny, Amy and Bernadette give Koothrappali dating advice when Emily reaches out to him after their breakup.
Amy is shocked at a revelation from Sheldon after she buys him a new laptop. Also, Koothrappali sells out Leonard and Wolowitz after they lie to their wives in order to attend an early screening of a movie.
Sheldon spills a secret of Leonard's when the two take a weekend cabin trip with Penny and Amy. Also, when Koothrappali goes overboard with pregnancy gifts, Wolowitz and Bernadette must draw the line.
Everyone must choose sides when a small argument between Leonard and Sheldon erupts into a heated fight during a group get-together.
The gang goes to a wine bar and runs into Penny's old boyfriend, Zack. Also, Bernadette gets stuck spending the evening with Sheldon when she can't go wine tasting with the group, and things don't go as planned when Koothrappali introduces his new girlfriend, Claire.
Sheldon hires Stuart to spend the day with Amy when he'd rather go to a movie screening. Also, Leonard's mother, Beverly, comes to town and Penny struggles to make a connection with her.
Chaos ensues when Leonard's recently divorced parents, Alfred and Beverly, and Sheldon's devoutly religious mother, Mary, come to town. Also, Wolowitz and Koothrappali think the government is out to get them when they are contacted about their guidance system.
Pamela Adlon(Halley Wolowitz)
Laura Spencer(Emily Sweeney)
Johnny Galecki(Leonard Leakey Hofstadter)
Jim Parsons(Sheldon Lee Cooper)
Simon Helberg(Howard Joel Wolowitz)
Kunal Nayyar(Rajesh Ramayan Koothrappali)
Mayim Bialik(Amy Farrah Fowler)
Melissa Rauch(Bernadette Marianne Rostenkowski)
Kevin Sussman(Stuart Bloom)
Sara Gilbert(Leslie Winkle)
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