Meet Meredith Grey, a woman trying to lead a real life while doing a job that makes having a real life impossible. Meredith is a first year surgical intern at Seattle Grace Hospital, the toughest surgical residency program west of Harvard. She and her fellow first-year interns were students yesterday; today they're doctors in a world where on the job training can be a matter of life and death. Such is the world of "Grey's Anatomy," ABC's midseason medical drama about young people struggling to become doctors and doctors struggling to remain human. It's a world filled with intensity, humor, sex and pain, in which the interns discover that neither medicine nor relationships can be defined in black and white -- real life only comes in shades of grey.
Meredith tries to figure out her relationship with Derek as George and Izzie move in with her.
Meredith Grey has discovered that the rules of residency are the same as the rules of life. Everything is a competition.
Cristina's encounter with a former nurse, now a patient at Seattle Grace, changes her forever; Derek and Meredith treat a construction worker who has miraculously survived an injury but is now faced with tough decisions about his future; and a patient recognizes Izzie from a lingerie ad, which makes her the subject of hospital gossip.
Meredith is overwhelmed causing her to make a mistake during surgery that could jeopardize her career.
Alex gains the trust of Annie, a nervous patient with an extraordinarily large tumor, only to humiliate himself in front of her later. Meanwhile Derek chooses Meredith to assist with an elderly Parkinson's patient who may need surgery -- but Bailey disapproves of their relationship and is determined to make Meredith suffer -- and tensions escalate between Burke and Shepherd.
George and Izzie find out about Mer and McDreamy while Cristina faces a test she's not quite prepared for.
Meredith grows increasingly dissatisfied with the unknown details of Derek's life. Meanwhile, Alex treats Devo, a patient whose religious beliefs jeopardize her chances for recovery; Izzie contemplates reconnecting with her estranged mother; Zoey, a pregnant woman in her 40s who's been diagnosed with cancer, disagrees with Cristina's medical advice; and the interns are mystified by Cable, a patient who's being treated for seizures and who thinks he's psychic.
An outbreak of a sexually transmitted disease affects several members of the hospital staff, prompting Chief Webber to call a meeting. Meanwhile, the chief reluctantly confides to Dr. Shepherd about his own medical concerns; Izzie and Cristina are worried by a patient's wife and daughter who are at odds over his care; Burke treats Bill, a college buddy whose medical diagnosis raises some questions regarding his wife's actions; and, just as Meredith and Derek grow more intimate, a bombshell is dropped, on the Season Finale of "Grey's Anatomy