As Meredith and Cristina discuss their relationship woes at the Emerald City Bar, their session of lamenting is interrupted when Joe, the bartender, collapses. And as Chief Webber recovers from brain surgery, he appoints one surgeon as interim chief - much to the dismay of another surgeon -- and he assigns George to report back with hospital gossip. While a devastated Meredith learns more about Derek and Addison's relationship, a confused Cristina tries to make decisions about her connection with Dr. Burke, on the season premiere of "Grey's Anatomy,
McDreamy wants to get back with Meredith. Addison wants to get back with McDreamy. Meredith just wants to keep it professional—with both of them.
Some very deep secrets are made painfully public when Meredith's mother, who suffers from Alzheimer's disease, is brought to Seattle Grace for a surgical procedure. Meanwhile, some frightening news about Cristina's health is brought out into the open, on Grey's Anatomy
As Cristina tries to recover, she proves to be a very difficult patient, and a visit from her mother doesn't improve her demeanor any. And Meredith's mother, Dr. Ellis Grey, has the hospital staff running in circles. Jeremiah, a cystic fibrosis patient, could benefit from Dr. Addison Shepherd's medical knowledge, but her involvement in his surgery could delay her highly anticipated departure from Seattle Grace Hospital, leaving Meredith and Derek's relationship hanging in the balance.
Meredith and Dr. Shepherd have to use more than medicine when a young woman's traditionalist, religious father forbids her to have a life-saving operation. Meanwhile, George and Alex are forced to perform surgery under less than ideal conditions in an attempt to save a patient's life, and its decision time for Derek and the two women in his life.
A massive train crash causes two victims to be impaled on the same pole. Izzie chooses between friendship and advancing her career.
Gossip is all the rage at Seattle Grace with Meredith feeling the brunt of it as a pregnant man comes into SGH and a heart spontaneously combusts!
McDreamy and Addison clash over their friend’s request for radical surgery while Meredith’s elderly patients restore her belief in true love.
The Thanksgiving holiday is more difficult for the interns and residents than any of them is willing to admit, as Izzie plans a big dinner at Meredith's -- but it remains to be seen who among the invited guests will actually show up. Meanwhile, George endures the O'Malley tradition of hunting turkeys with his less-than-sophisticated family, and Meredith treats a patient who's been in a vegetative state for 16 years.
Meredith & lsquo;s one night stand has an erection that just won’t quit, Izzie catches Alex in the act with Olivia and Cristina gets keyed by Burke.
Cristina has little sympathy for Constance Ferguson, a prison inmate who jeopardizes her health just to get out of solitary confinement.
A boy needs a heart transplant but doesn't want it, and an argument over his treatment exposes philosophical differences between Burke and Cristina.
Izzie seems to be getting over Alex when she shares an undeniable chemistry with Denny Duquette, a patient who's awaiting a heart transplant.
The truth is in short supply as Meredith and Cristina lie to each other about the status of their relationships. George is given the unpleasant task of discharging an elderly patient who's no longer sick, but refuses to leave the hospital; and Alex learns his fate after re-taking his medical exams.
The nurses at Seattle Grace Hospital go on strike, leaving the doctors to fend for themselves.
Meredith's fears that she is in for a bad day are realized when a medical case arrives at SGH that threatens the lives of everyone in the O.R.
Despite the best efforts of the Seattle Grace staff, the code black situation escalates.
Meredith and Burke treat a patient who probably won't survive surgery and the patient asks Meredith to videotape him venting.
No one knows what transpired between George and Meredith but George and Meredith—and they aren't talking.
It becomes a bad day for Cristina when Bailey instructs her to take care of her baby.
After four deaths in the morning, every doctors' personal superstitions and rituals come into focus.
George begins to overstay his welcome at Burke's apartment, Meredith learns a secret about her father and Alex gets a lesson in bedside manners.
Derek and Addison aren't having the best sex, something Meredith learns of by accident, just before Finn asks her out.
Derek is mad at Meredith, George is living back in the house, though still not talking to Meredith and Cristina begins the day on a rush.
A shooting at a nearby restaurant bombards the hospital with plenty of gunshot victims—and one intended victim that didn't get shot.
Burke has been shot and Izzie has just cut Denny's LVAD wire. George, Meredith, and Cristina all wind up helping Izzie keep Denny alive.
In the conclusion of the second-season finale, Denny proposes to Izzie after receiving his new heart and Burke experiences hand tremors after awakening from his surgery. Meanwhile, the interns plan the prom for the Chief's niece (Tessa Thompson) while awaiting their fateful meeting with the Chief; George and Callie have a heart-to-heart about his feelings for her; and Meredith and Derek must make a decision about Doc. Mer also must decide between Derek and Finn (Chris O'Donnell).