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- TV Show Ended -
There is no Next Episode of House planned.
House and Cuddy explore the ramifications of their feelings and attempt to make a real relationship work. Meanwhile, due to a colleague's illness, Princeton Plainsboro is left without a neurosurgeon on site, threatening the hospital's accreditation as a Level 1 Trauma Center.
When Della, a seemingly healthy and active 14-year-old, suddenly collapses during a skateboarding exhibition, House and his team struggle to diagnose her condition and reassure her parents who already have to cope with their son's terminal illness.
When Alice, the author of a popular children's book series, inexplicably suffers from a seizure moments before an attempt to take her own life, the Princeton Plansboro team faces the challenges of evaluating both her underlying medical conditions, as well as her unstable psychological state.
When a patient named Margaret McPherson is admitted to Princeton Plainsboro after suffering severe and uncontrollable vomiting, House and the team make unexpected discoveries about her identity as they assess her symptoms. Meanwhile, a visit from House's massage therapist forces House and Cuddy to confront the reservations in their relationship.
After a newborn experiences inexplicable breathing problems and liver failure, House and the team look at the baby's mother, Abbey's, own medical history for possible clues. Meanwhile, following Cuddy's directive, House challenges Foreman and Taub to hire a female doctor to join the team. When Cuddy asks House to babysit her daughter, both House and Wilson learn a few hard lessons in parenting.
It's election season, and in the midst of a tight campaign, an incumbent New Jersey senator's campaign manager falls ill with liver failure and temporary paralysis. Cuddy pushes House to add a female doctor to his team by hiring brilliant third-year medical student Martha Masters in Thirteen's absence.
After a 200-year-old medicine jar found on an off-shore shipwreck shatters in a teenage girl's palm, she is admitted to Princeton Plainsboro for symptoms closely linked to smallpox. Meanwhile, Wilson and Sam comfort a 6-year-old chemotherapy patient who prompts them to examine their relationship.
Science and faith are called into question when a patient is admitted to the hospital after he starts coughing up blood while be crucified. Meanwhile, Taub questions his wife Rachel about her relationship with an infidelity support group member and the team attends a co-worker's wedding where Wilson's relationship with Sam takes an unexpected turn.
When a man puts his life on the line to save a stranger who fell onto the subway tracks, he emerges from the dramatic scene miraculously unscathed but then suddenly collapses. Meanwhile, House tries to avoid Cuddy's birthday dinner with her opinionated mother Arlene and Taub draws unexpected attention when his face graces billboards advertising the hospital.
A teenage military trainee at a juvenile offender training camp suffers peculiar symptoms after enduring an intense training course, and mysteriously, his drill sergeant is soon admitted for similar symptoms. Sensing Cuddy's stress over her daughter Rachel's enrollment at a prestigious preschool, House secretly prepares Rachel for observations and reveals a soft spot for the toddler.
Cuddy's mother, Arlene, is admitted to Princeton Plansboro after complaining about unusual symptoms, but stubborn Arlene insists that House be removed from the case, forcing House to come up with non-conventional - and illegal - means to treat his patient.
When a waitress with a perfect memory suffers temporary paralysis, her older sister visits her in the hospital, which triggers high stress levels and even more health complications. Meanwhile, Foreman volunteers to help Taub prepare for a medical examination, and House, determined to help Wilson get back in the dating scene, discovers Wilson's secret new companion.
House participates in a school's Career Day and breaks a few rules by sharing explicit medical stories. Waiting outside the principal's office, he meets two fifth-grade students who assess House's relationship woes and try to help him understand how his selfish antics get in the way of showing Cuddy how he really feels.
A patient is admitted after breaking out in a severe rash triggered by caustic chemical exposure at his blue-collar job. As the team treats him, they discover that he has led his wife to believe that he is still maintaining his once-lucrative real estate career.
Tension reaches new heights when Cuddy faces sobering news that propels her to reevaluate her priorities. While House is distracted by his concern for Cuddy's well-being, the team treats a teenage patient whose worsening symptoms and suspicious body scars indicate more than just physical illness.
A young professional champion bullfighter is admitted for treatment after being attacked by a bull. After conducting multiple inconclusive tests, the team enlists House's advice outside of the hospital while he attends to a few issues away from the case.
A young homeless man who is a former drug addict is found in a park showing signs of olfactory impairment and horrific scars and burn marks on his chest. With an uncertain identity and the patient's severely worsening conditions, the team looks to the patient's personal records and family history in order to understand his detachment.
House discovers where Thirteen has been and meets her as she is released from prison. He has a duel purpose for being there: he wants to know what she did to end up in jail, and he needs her help to win a local spud-gun shooting contest. Meanwhile, at the hospital, the team treats a science teacher suffering from severe respiratory illness
Masters faces a career crossroads on her last day as a medical student and struggles with the choice to continue on the path to become a surgeon or to accept the rare opportunity to join House's team officially. Meanwhile, the team treats a 16-year-old girl who inexplicably collapsed days before embarking on an ambitious sailing tour around the globe.
After suffering partial paralysis while searching for a long-lost love, lottery winner Cyrus Harry is brought to Princeton Plainsboro for treatment by House and the team. Cuddy's mother threatens to sue the hospital for malpractice, jeopardizing both Cuddy and House's medical licenses.
When House and Wilson bet on a boxing match and disagree over the outcome, Wilson gives him exactly one day to pay up or prove him wrong. House presses the boxer for more information to help prove his case and ends up attempting to breathe new life into the losing fighter's career. Meanwhile, the team begins to suspect House may have another type of drug problem.
Thirteen's ex-con friend, Darrien, arrives at Thirteen's apartment unannounced and in need of urgent medical attention. When she finds out her friend has relapsed into drug use, Thirteen promises not to take her to the hospital where the cops could find her and instead turns to Chase in desperation.
Well-known performance artist Afsoun Hamidi is admitted to the hospital, but when the team learns that her symptoms may have been self-inflicted as part of a documentary for her latest performance piece, they begin to question whether treatments are necessary and if they are unwittingly participating in the creation of a piece of her art.