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- TV Show Ended -
There is no Next Episode of NYPD Blue planned.
John Kelly takes on the mob after his partner, Andy Sipowicz, is shot by a vengeful gangster. Kelly's wife wants a divorce.
As Sipowicz slowly recovers from his wounds he says that he cannot remember who shot him. Kelly appears in court on behalf of a man whose son was killed in a drive-by shooting. Laura Kelly's neighbour, Josh Goldstein, carries a concealed weapon hoping to surprise the person who mugged him.
Kelly and Sipowicz investigate a strangulation murder as fallout from the Marino case implicates Licalsi's father in wrongdoing. Kelly acts as a bodyguard to the wife of a millionaire and Sipowicz exacts his own unique revenge on Giardella.
Kelly and Sipowicz investigate a double homicide at a liquor store. Mrs. Wagner seeks revenge against her husband and Goldstein fatally ignores Kelly's warnings about confronting criminals.
Martinez discovers that his brother has lost his job and continuing to use drugs. As James plans to send him to a Detox program, the two encounter the building superintendent who according to Roberto is forcing Tenants out of the building for money. Martinez then discovers that the superintendent turns out to be an officer from another precinct named Jack Hanlon who came up through the NYPD with John Kelly's father. A gambling addicted detective spends the last of his savings staging elaborate practical jokes at the precinct much to the ire of Lt. Fancy. Following the death of another tenant in Roberto's building, a disgusted Kelly helps Martinez in bringing Hanlon to justice saving Martinez from spending the rest of his career in IAB.
Kelly is forced to arrest a close friend after a dispute on a basketball court results in death. Sipowicz suspects a husband may be concealing the truth in the drive-by shooting of his wife. Licalsi's quick thinking saves Kelly's life during a drugs raid.
Kelly and Sipowicz investigate the disappearance of a young boy. Sipowicz's estranged son announces his engagement to a woman that raises the father's suspicions. Laura is the sole witness when an assassin ambushes Giardella. A man who claims to be awerewolf may have witnessed a murder.
Kelly interrogates a man suspected of committing a string of taxi robberies, one of which resulted in the shooting death of a cab driver. Sipowicz goes undercover at a topless bar. Lt. Fancy hires Donna Abandando, a civilian, as the precinct's receptionist and administrative assistant for the squad.
When Roberto, Martinez's brother, dies of a drug overdose, their father vows revenge. Licalsi receives a blackmail threat from the mob. Medavoy, seeking a distraction from his troubled marriage, accepts Donna's offer to go ice skating.
Kelly investigates the brutal robbery-murder of a wealthy family and a Hollywood screenwriter reports that his Oscar has been stolen. Meanwhile, Licalsi ignores Kelly's advice and informs Lastarza that she is being blackmailed by the mob.
Fancy is harassed by Borough Commander Haverill who accuses him of mismanaging the detectives. Kelly and Sipowicz investigate the kidnapping of a young girl whilst a destitute mother with a questionable past agrees to testify against a man who is suspected of committing armed robbery. Sipowicz realizing that Haverill is trying to move Fancy out for bogus reasons blackmails Haverill over an unsolved mob murder. The precinct staff collects gifts for a Christmas party they are hosting for some needy children.
A manhunt ensues when Tommy Linardi's dead body is discovered inside a nightclub. A robber uses a fake ATM to rob unsuspecting customers of their savings and Fancy tries retaining temporary custody of a young boy whose mother only recently finished a drug rehabilitation program.
Detectives investigate the shooting death of a man whose wife recently transferred to the precinct. A woman claims she wants her husband prosecuted for spousal abuse but never follows through on her threat. Elsewhere, Medavoy begins an affair with Donna.
The detectives search for a cross-dressing killer, while a sexual assault victim fears her husband will blame the attack on her provocative style of dress. Sipowicz's dental appointment is interrupted when a doctor threatens to commit suicide.
A detective becomes the prime suspect in the suspicious suicide of a police informant. Laura believes Kelly may have overlooked evidence in a homicide investigation and a detective obsessed with his physique is tested for substance abuse.
The girlfriend of a terminally ill millionaire is blackmailed by her ex-lover and Sipowicz investigates the robbery of a disabled Vietnam veteran.
The detectives investigate the slaying of a young black teenager whose father takes matters in his own hands when a likely suspect escapes. Sipowicz suspects a private investigator is taking advantage of a man whose daughter disappeared 2½ years earlier.
After a witness is gunned down in the street, the detectives scramble to save their case against the two brothers who have also planned a hit on Laura.
Kelly, Medavoy, and Martinez lead a search for a girl's body in a Staten Island landfill, finding another body in the process. Sipowicz attempts to clear Andy Jr.'s name after his son is arrested for selling drugs.
Kelly and Sipowicz investigate the death of one of Charlie Lear's many mistresses. Licalsi receives an unexpected promotion. Sipowicz has a rough night after meeting Costas' family at a birthday party. Fancy's wife tells her husband that she is pregnant.
Medavoy and Martinez narrowly escape injury when a disgruntled driver tries to shoot them, then face the wrath of angry African Americans who believe that they have killed a black man without reason. Licalsi confesses to murdering Marino and his driver and Andy attends an Alcoholics Anonymous meeting. Meanwhile, Medavoy moves out once again after he discovers his wife has been cheating on him.
Detectives investigate the murder of a priest whose body was discovered in a park frequented by male prostitutes. Sipowicz reopens an investigation into the disappearance of a friend's daughter. While Kelly and Robin become lovers, Licalsi wins release on bail.