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There is no Next Episode of NYPD Blue planned.
The detectives investigate the shooting death of a man whose brother is a registered sex offender; and when Captain Fraker's trial gets underway, Sipowicz worries that his own testimony may have harmed the prosecution's case.
Sipowicz and Clark investigate the death of a transvestite whom a friend insists was having a relationship with a married man; a surgeon's hand is badly cut during a robbery; and Rodriguez testifies in the Fraker trial.
The detectives search for clues when a group of perpetrators torture a man for no apparent reason; a woman reports her husband as missing, but Sipowicz and Clark suspect she's not being completely forthcoming; and Fraker testifies in court.
The detectives investigate the strangulation death of a former porn star; a thirteen-year-old boy holds the key in implicating his father in his mother's murder; and the jury reaches a verdict in the Captain Fraker trial.
The detectives investigate a strangulation murder that may be tied to one of Diane Russell's cases; Russell consults a doctor when she discovers a lump in her breast; Medavoy and Jones investigate an arson linked to two boys.
Sipowicz, Russell, and Clark attempt to connect the murder of a young woman to two other killings; Medavoy and Jones investigate the shooting death of a mother whose children feared her.
A woman survives the serial killer's attack, and her account prompts the detectives to focus on Carlin, his partner, and a bodyguard; Medavoy and Jones investigate when an off-duty officer kills a man; and McDowell comforts Russell during a biopsy.
When another woman is murdered by the serial killer, the detectives arrest a suspect... and discover the killer's identity; and expecting a baby, Sipowicz and McDowell decide to get married.
Sipowicz and Clark search for two burglars who terrorized a retired cop and his wife; Medavoy and Jones assist an author who wrote a book on how to avoid paying income taxes; and Jones deals with Michael's father.
A man armed with a bomb walks into the station house and handcuffs himself to McDowell; unless the detectives release a Russian mobster from jail in one hour, the bomb will detonate.
When a Jewish jewelry-store owner is murdered, the detectives focus their investigation on two suspects: a Caucasian man who converted to Islam, and a rap star whose expensive jewelry turned out to be fake.
Sipowicz and Clark search for an African-American driver who fled the scene of a hit-and-run accident after unwittingly running over an Italian mobster's young daughter.
Sipowicz and Clark investigate the shooting death of a jogger who'd been having an affair with a police officer; and Medavoy and Jones search for answers when the body of a comedy club owner is found in the trunk of a stolen car.
A new detective, Stan Hatcher, joins the squad; the detectives investigate a shooting death that Hatcher believes is linked to a dispute between gang members; and a man insists that his young daughter has been kidnapped.
A kidnapping victim's startling statement clues Andy and John in on a serial sadist keeping women locked in a dungeon somewhere in New York. Meanwhile, a routine robbery investigation takes a saucy turn for Medavoy after he makes an unlikely connection with the 60-year-old victim.
Sipowicz searches for the truth when Hatcher is shot by a man who mistook him for a burglar; and a former pharmacist dies in a flophouse when someone fires a bullet into his room.
Andy's off-duty and slightly underhanded work to prove that Hatcher killed his own wife lands him a transfer out of the 15th precinct and into the Bellevue Morgue engineered by Detective Hatcher. Meanwhile, the squad is up to their whips and chains after a dominatrix is found murdered.
Haywood reopens an 18-year-old case that has Andy reliving a major mistake in his career. Meanwhile, Sipowicz and Clark investigate the death of a man whose brother was pursued by a bounty hunter. Elsewhere, Ortiz gets a new partner, Detective Kelly Ronson, who ends up lending an unusual hand during the hunt for the child an ex-con had to give up before going to prison.
A man's gunshot-induced amnesia causes Jones and Medavoy to concoct an unconventional way to nail his assailant. Meanwhile, a man Sipowicz put away twenty years ago for raping and murdering a 12-year-old girl goes free after DNA testing exonerates him, and Ortiz and Ronson bust a gruesome underground network pre-teen prostitution ring.
Andy and John approach Mrs Clifton for help with her daughter's murder. Jennifer turns up out of the blue, apparently off her meds. A man is shot, apparently over a church and a video tape.
Teacher David Lewis comes into the squad-room to talk about Cindy Clifton and a support group that he ran that she was a part of. Sipowicz and Clark let him go but send off some of his left behind chewing gum to DNA for testing. Jones goes to court as its the day when Michael is to testify against his father. Ortiz and Ronson go to the scene where tourist Ned Applebaum has been mugged and lost his wife's $35,000 necklace. Ortiz and Ronson eventually find out that Ned met a lady friend on the Internet and he was going to meet her in Little Italy when he was mugged. He was going to loan her the necklace so that she could use it as collateral for a loan for her sick child. The detectives get the PO Box number where Applebaum had sent previous gifts to his lady friend. Ortiz and Ronson go to the apartment of the owner of the PO Box. He is a day trader/con artist who they discover took advantage of Ned Applebaum. They get the necklace back and Ned is forgiven by his wife. Later, Gibson tells Sipowicz and Clark that David Lewis was found DOA in his apartment. They go to the scene and try to determine whether the death was a suicide or not. Sipowicz tries to decide how to proceed with the investigation of Lewis's death; both he and Clark believe that Brockhurst might be involved. Clark gets a call about Dr. Jennifer Devlin and goes to the hospital. The doctor tells her she needs to remain restrained for now, but he is allowed to see her as long as he doesn't loosen her restraints. Sipowicz finds Brockhurst and tells him of his theory that he killed David Lewis. Brockhurst doesn't admit to anything, but tells Sipowicz he is going to be able to sleep tonight now that the case is closed.
Sipowicz investigates a murder involving the victim's current husband and ex-husband; a longtime informant gives Ronson information about an illegal gun shipment, but the suspect's father is being followed by the FBI; Jones gets into a fight with Craig after he's acquitted of murder charges; and Sipowicz is the proud father of a baby boy.