A trip to Napa concludes with tensions at a high. Back in the OC, Vicki and Brooks consider some unconventional cancer treatments, Meghan puts the final touches on her first OC charity event while Heather faces the harsh reality of going over budget on her dream home. Meanwhile, Shannon receives some shocking news and unresolved issues between her and Meghan become the topic of the ladies' scrutiny at Meghan's JDRF charity event.
Vicki gets a phone call that forever changes her life.Shannon offers an olive branch to Meghan when she hosts a Bunco party at her house. Meanwhile, Meghan moves into another house and Heather has an unorthodox date night with Terry that gets a little bloody.
The passing of Vicki's mother sends shock waves through the group, causing everyone to reflect on family; Tamra celebrates the birth of her granddaughter; Shannon continues to repair her marriage; Meghan tries to create a lasting memory for Hayley.
Vicki enlists the powers of a medium to try and communicate with her mother. Shannon discovers that to lose physical weight, she has to do more than just exercise, she must deal with the weight of her emotions too. Meghan tries to teach her step daughter responsibility but learns a lesson about parenting instead. While Tamra and Eddie struggle to work together at the gym, Heather is eager to start a new project with Terry. All the ladies come together for a fun night of bowling and a surprise announcement.
After Meghan hosts a couples' game night, her husband's absence ends up being the main topic of discussion. Shannon and David meet with their therapist.
The ladies get the chance to swim with sharks as they take a Tahitian getaway, but Meghan finds out that the sharpest bite comes from the other wives.
Vicki and Shannon grow closer after they learn details of an affair while also dealing with hangovers. The other ladies manage to get themselves into deep water while on an excursion.
Back in the OC, Shannon and David discover that disciplining their kids is easier said than done. Vicki learns that Brooks has made a life altering decision, to stop chemo and try a radical new approach. Meanwhile, Tamra's psychic makes a shocking claim leaving the ladies in disbelief.
Meghan, Heather, Tamra and Shannon head to NASCAR while Vicki enjoys a birthday getaway with Brooks. Shannon tries to put on a happy face during her birthday dinner. Heather throws a luncheon at her unfinished home, where Meghan confronts the OG of the OC.
As Shannon seeks to make sense of her friendships, Tamra looks to a higher source to improve her son's troubled relationship. Meanwhile, Heather's Evine launch in Minnesota takes a turn for the worse as Terry botches the rehearsal. After a trip to the doctor with Brooks, Vicki tries to put an end to the cancer debate, but when Meghan hosts a viewing party in celebration of Heather's big night, a new revelation about Brooks has everyone stunned.
Vicki's daughter, Briana, meets Tamra for lunch and imparts shocking information about Brooks; Shannon confides in Heather and Tamra; the women prepare for Tamra's baptism in unconventional ways.
In the season finale, the ladies gather together to witness Tamra's baptism, but with the constant questions and confusion surrounding Brooks' cancer, Vicki is the one who feels crucified. And after an evening of avoidance, Shannon and Vicki come face-to-face when Shannon discovers that Vicki has committed the ultimate betrayal.
The reunion kicks off with the Housewives gathering on the couch to rehash the past year. Meghan makes her mark on her first reunion by clashing with Vicki over her step-mom comments and demonstrating what "Judgey Eyes" really looks like. Tamra reveals the heartbreaking family drama she has been keeping secret for the past year. Plus, a Housewife from the past speaks her mind about Tamra's religious transformation and Vicki shares hilarious memories of her late mother.
On part two of the reunion, the ladies get wild and crazy looking back at the best OMG moments of season 10. While Shannon faces scrutiny about her marriage and David's affair, tensions rise when Heather gets heated about Vicki's betrayal of Tamra. Jim Edmonds also joins the ladies on the couch and is put in the hot seat about his marriage to Meghan. Briana makes an appearance and is no holds barred when it comes to her opinions about Brooks.
The reunion concludes as the women confront Vicki with their doubts about Brooks' cancer. Shannon provides details regarding the validity of the PET/CT Scan, Tamra and Heather confront Vicki about the possibility of being blackmailed, and the ladies have strong reactions to Andy's interview with Brooks. Vicki makes a stunning revelation that has everyone doubting what they've heard.
Andy Cohen interviews Brooks Ayers about the allegations regarding his health.
Never-before-seen footage from season 10 includes Shannon's unique luncheon, a wild ride in Tahiti and revelations about Vicki's history with Brooks.